Which channel does NOT have a connection to the eyes?

The large intestine is the correct choice as it does not have a connection to the eyes in the context of traditional Chinese medicine (TCM) or anatomy. In TCM, each organ is believed to be associated with specific sensory organs.

The heart is connected to the tongue, the small intestine is associated with the eyes, and the liver is linked to the eyes as well through its role in nourishing them. The eyes are thought to rely on the liver’s ability to maintain good blood flow and overall function, which is why the liver is particularly emphasized in eye health.

The large intestine, on the other hand, primarily focuses on the processing of waste and does not have a direct relationship with eye function or health. Thus, it stands apart from the other listed organs in the context of connections with the eyes.